![]() ![]() N-Acetylcysteine: A Powerhouse Natural Remedy. A Woman's Time on Apr 12, 2014. Many people are aware of the use of N-acetyl cysteine. Effect of N-acetylcysteine on the Murine Model of Colitis Induced by Dextran Sodium Sulfate Through Up-Regulating PON1 Activity. N- Acetyl Cysteine Effectiveness, Safety, and Drug Interactions on Rx. List. What other names is N- acetyl Cysteine known by? Amino acids are the building blocks of proteins. N- acetyl cysteine has many uses as medicine. N- acetyl cysteine is used to counteract acetaminophen (Tylenol) and carbon monoxide poisoning. It is also used for chest pain (unstable angina), bile duct blockage in infants, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Alzheimer's disease, allergic reactions to the anti- seizure drug phenytoin (Dilantin), and an eye infection called keratoconjunctivitis. It is also used for reducing levels of a type of cholesterol called lipoprotein (a), homocysteine levels (a possible risk factor for heart disease) and the risk of heart attack and stroke in patients with serious kidney disease. Men's Weight Loss Plans; Men's Build Muscle Plans; Women's Weight Loss Plans. Failure of N-acetylcysteine to reduce low-density lipoprotein oxidizability in healthy subjects. Eur J Clin Pharmacol 1992;43. Some people use N- acetyl cysteine for chronic bronchitis, chronic obstructive pulmonary disease (COPD), hay fever, a lung condition called fibrosing alveolitis, head and neck cancer, and lung cancer. It is also used for treating some forms of epilepsy; ear infections; complications of kidney dialysis; chronic fatigue syndrome (CFS); an autoimmune disorder called Sjogren's syndrome; preventing sports injury complications; radiation treatment; increasing immunity to flu and H1. N1 (swine) flu; and for detoxifying heavy metals such as mercury, lead, and cadmium. ![]() N- acetyl cysteine is also used for preventing alcoholic liver damage; for protecting against environmental pollutants including carbon monoxide, chloroform, urethanes and certain herbicides; for reducing toxicity of ifosfamide and doxorubicin, drugs that are used for cancer treatment; as a hangover remedy; for preventing kidney damage due to certain X- ray dyes; and for human immunodeficiency virus (HIV). Healthcare providers give N- acetyl cysteine intravenously (by IV) for acetaminophen overdose, acrylonitrile poisoning, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), kidney failure in the presence of liver disease (hepatorenal syndrome), chest pain in combination with nitroglycerin, heart attack in combination with nitroglycerin and streptokinase, and for helping to prevent multi- organ failure leading to death. N- acetyl cysteine is sometimes inhaled (breathed into the lungs) or delivered through a tube in the throat to treat certain lung disorders such as pneumonia, bronchitis, emphysema, cystic fibrosis, and others. Effective for.. Acetaminophen (Tylenol) poisoning. N- acetyl cysteine is effective in reducing the death rate and preventing the permanent harm caused by acetaminophen poisoning. For this use, N- acetyl cysteine given by mouth is as effective as N- acetyl cysteine given intravenously (by IV). Collapse of part or all of a lung (atelectasis). N- acetyl cysteine helps treat collapsed lungs caused by mucus blockage. Diagnostic lung tests. N- acetyl cysteine is helpful when used to prepare people for diagnostic lung tests. Care of people with a tube in their windpipe (people who have undergone a tracheostomy). N- acetyl cysteine helps prevent crusting in people with a tube in their windpipe. Possibly Effective for.. Chest pain (angina). Taking N- acetyl cysteine by mouth or injecting it intravenously (by IV) seems to improve chest pain when used with the drug nitroglycerin. Intravenous N- acetyl cysteine seems to help prevent nitroglycerin tolerance. Oral N- acetyl cysteine might help prevent nitroglycerin tolerance, but results are conflicting. Bipolar disorder. Taking N- acetyl cysteine by mouth seems to help reduce depression symptoms in people with bipolar disorder. Air passage swelling (bronchitis). N-acetylcysteine -- a form of the amino acid cysteine -- has powerful health benefits. It may even support weight loss. But since studies so far have only. Weight Loss Panel (Comprehensive). The Overlooked Compound That Saves Lives May 2010. In this article, you will discover the latest research on N-acetyl cysteine (NAC), a readily available. Dubs JG, Roederer M, Anderson M, Green A. Glutamine antioxidant supplementation increases body cell mass in AIDS patients with weight loss. N-acetylcysteine (NAC) is a commonly used compound in nutritional supplements and pharmaceutical drugs. It is frequently found in medications used to expel mucus from the lungs, trachea and bronchi. A derivative of the amino. ![]() Taking N- acetyl cysteine by mouth seems to reduce shortness of breath in people with air passage swelling due to mustard gas exposure. Also, taking N- acetyl cysteine by mouth for 3- 6 months seems to prevent flare- ups in people with persistent air passage swelling. However, taking it for less time does not seem to be effective. A lung disease called chronic obstructive pulmonary disease (COPD). Taking N- acetyl cysteine by mouth seems to decrease flare- ups by about 4. COPD. However, it might increase the risk of blockage of the breathing tube. Kidney problems caused by dyes used during some X- ray exams. Taking N- acetyl cysteine by mouth seems to help prevent kidney problems caused by dyes used during some X- ray exams in people with severely reduced kidney function (kidney insufficiency). It might help prevent these problems in people with moderately reduced kidney function. It does not seem to lower the risk of kidney problems caused by dyes used during X- ray exams in people with normal kidney function. ![]() ![]() Serious kidney disease. Taking N- acetyl cysteine by mouth seems to help prevent problems, such as heart attack and stroke, in people with serious kidney disease. The risk reduction can be as much as 4. However, N- acetyl cysteine doesn't reduce the overall risk of death or the risk of death from heart disease in these people. Epilepsy seizures. Taking N- acetyl cysteine by mouth seems to help treat a certain type of epilepsy seizure. A lung disease called fibrosing alveolitis. Taking N- acetyl cysteine by mouth seems to improve lung function in people with fibrosing alveolitis. High levels of homocysteine. Taking N- acetyl cysteine by mouth seems to reduce homocysteine levels, a possible risk factor for heart disease. High levels of blood fat. Taking N- acetyl cysteine by mouth seems to reduce levels of a blood fat called lipoprotein(a) in people with high levels of this blood fat at baseline. Ifosfamide (Ifex) side effects. Taking N- acetyl cysteine by mouth seems to help prevent side effects of ifosfamide (Ifex), which is used for certain types of cancer. However the drug mesna (Mesnex) seems to work better than N- acetyl cysteine. Flu. Taking N- acetyl cysteine by mouth seems to reduce flu symptoms. Heart attack. Injecting N- acetyl cysteine intravenously (by IV) seems to help maintain heart function in people having a heart attack when given with the drugs nitroglycerin and streptokinase. Tolerance to nitrate. Injecting N- acetyl cysteine intravenously (by IV) seems to help prevent tolerance to nitrate. Oral N- acetyl cysteine might help prevent nitrate tolerance, but results are conflicting. Hair pulling. Taking N- acetyl cysteine by mouth seems to decrease hair pulling by up to 4. Possibly Ineffective for.. Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease). Injecting N- acetyl cysteine intravenously (by IV) doesn't seem to improve ALS symptoms. Breathing problems in premature infants. Giving N- acetyl cysteine through a hole in the windpipe does not seem to prevent breathing problems in premature infants. Cystic fibrosis. Taking N- acetyl cysteine by mouth or breathing it in doesn't seem to improve lung function in people with cystic fibrosis. However, N- acetyl cysteine might reduce markers of swelling in people with cystic fibrosis when taken by mouth in high doses. Doxorubicin side effects. Taking N- acetyl cysteine by mouth doesn't seem to prevent or treat side effects of doxorubicin, a drug used to treat certain types of cancer. A condition that causes sensitivity to light (Erythropoietic protoporphyria, EPP). Taking N- acetyl cysteine by mouth doesn't seem to prevent sensitivity to light in people with EPP. Hepatitis. Taking N- acetyl cysteine by mouth doesn't seem to help treat viral hepatitis. It also doesn't seem to improve response to interferon therapy in people with hepatitis C. However, it might help prevent relapses in people with hepatitis C. HIV/AIDS. Taking N- acetyl cysteine by mouth doesn't seem to improve immune function or reduce the amount of virus in the body in most people with HIV. However, it might improve immune function in people with HIV who have low levels of glutathione, a chemical in the body that is formed from N- acetyl cysteine. Low blood pressure. Taking N- acetyl cysteine by mouth doesn't seem to reduce the risk of kidney failure in people with long- term low blood pressure. Kidney disease. Taking N- acetyl cysteine doesn't seem to improve long- term kidney disease. Liver transplant. Injecting N- acetyl cysteine intravenously (by IV) during surgery to donate a liver and keeping the liver in a cold liquid containing N- acetyl cysteine before the liver transplant doesn't seem to prevent transplant rejection. Pancreas swelling (pancreatitis). Taking N- acetyl cysteine by mouth doesn't prevent pancreatitis in people undergoing a certain diagnostic procedure that can cause pancreas swelling. Also, injecting N- acetyl cysteine intravenously along with selenium and vitamin C doesn't seem to prevent pancreas dysfunction in people with serious pancreatitis. Bone loss after menopause. Taking N- acetyl cysteine by mouth doesn't seem to prevent bone loss after menopause. Recovery after surgery. Taking N- acetyl cysteine by mouth or injecting it intravenously (by IV) doesn't seem to reduce the risk of heart attack, stroke, kidney injury, or death after heart surgery. N- acetyl cysteine might help prevent abnormal heartbeats after heart surgery, but results are conflicting. Likely Ineffective for.. Alzheimer's disease. Taking N- acetyl cysteine by mouth doesn't improve symptoms of Alzheimer's disease. Head and neck cancer. Taking N- acetyl cysteine by mouth doesn't prevent new tumors or improve survival in people with head and neck cancer. Lung cancer. Taking N- acetyl cysteine by mouth doesn't prevent new tumors or improve survival in people with lung cancer. Treating organ failure. Injecting N- acetyl cysteine intravenously (by IV) might increase the risk of death in people with multiple organ failure. Insufficient Evidence to Rate Effectiveness for.. A life- threatening lung condition (acute respiratory distress syndrome, ARDS). Some research shows that injecting N- acetyl cysteine intravenously (by IV) reduces the risk of death and improves some aspects of lung function in people with ARDS. However, conflicting research exists. Adrenoleukodystrophy (ALD). N- Acetyl Cysteine (NAC): Uses and Risks. Why do people take NAC? As a prescription drug, doctors use NAC to treat acetaminophen overdose. It may also help break up mucus in people with some lung diseases, like chronic bronchitis. As a supplement, some people use NAC to try to protect the liver. There's evidence it can help prevent liver damage caused by some cancer drugs. Some animal studies have shown that NAC may help protect against some cancers. However, there is little evidence that it would have anti- cancer benefits in people. There's mixed evidence about whether NAC helps with other conditions, like infertility, the flu, cystic fibrosis, liver disease, angina, HIV, and some eye conditions. More research is needed. Optimal doses of NAC as a supplement have not been set for any condition. Quality and active ingredients in supplements may vary widely from maker to maker. This makes it very hard to set a standard dose. There are standard doses for prescription uses of NAC. These depend on the condition that is being treated. Ask your doctor for advice. What are the risks? Tell your doctor about any supplements you're taking, even if they're natural. That way, your doctor can check on any potential side effects or interactions with medications. Side effects. Extremely high doses - - 6. NAC may not be safe for people with asthma or with severe liver or kidney disease. If you're pregnant or breastfeeding, you must check with a doctor before using NAC supplements. Interactions. If you take any medicines regularly, talk to your doctor before you start using NAC supplements. They could interact with nitroglycerin or other medications. The U. S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Unlike drug manufacturers, the makers of supplements don.
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